Can you just leave it at that, or do I need to go into my life story? I don't want to hear about all the options I have for acquiring a child. I know about IVF, IUI, donor sperm, donor eggs, surrogates, adoption, fostering and making one out of wood! None of those are options for me (us)! Leave it alone, already! The only acceptable answer is "Oh." Unless you know that I wanted to have kids, in which case it's "Oh, I'm sorry."
I also don't want to hear about how lucky I am not to have to deal with dirty diapers, midnight feedings, homework, tuition, car insurance... This is not helpful! The truth is, I don't care about any of those things, and would have GLADLY suffered through them for the chance to be a mother. But I wasn't given that chance. Smile and nod... and walk away or change the subject.